diff --git a/pipewire-v4l2/src/pipewire-v4l2.c b/pipewire-v4l2/src/pipewire-v4l2.c
index fbe71baea..88702f95b 100644
--- a/pipewire-v4l2/src/pipewire-v4l2.c
+++ b/pipewire-v4l2/src/pipewire-v4l2.c
@@ -672,7 +672,7 @@ static void registry_event_global(void *data, uint32_t id,
 	const struct global_info *info = NULL;
 	struct pw_proxy *proxy;
 	const char *str;
-	uint32_t serial = SPA_ID_INVALID, dev;
+	uint32_t serial = SPA_ID_INVALID, dev, req_serial;
 
 	if (spa_streq(type, PW_TYPE_INTERFACE_Node)) {
 
@@ -692,6 +692,11 @@ static void registry_event_global(void *data, uint32_t id,
 		    !spa_atou32(str, &serial, 10))
 			return;
 
+		if ((str = getenv("PIPEWIRE_V4L2_TARGET")) != NULL
+				&& spa_atou32(str, &req_serial, 10)
+				&& req_serial != serial)
+			return;
+
 		dev = find_dev_for_serial(serial);
 		if (dev != SPA_ID_INVALID && dev != file->dev_id)
 			return;