WLED supports the E1.31 (sACN) realtime light protocol. I highly recommend the LedFx project! 170 LEDs (510 DMX channels) are supported per universe. You can use up to 9 adjacent universes which is a total of more than the maximum 1500 LEDs WLED can drive.
For a fluent 25ms (40fps) or more framerate, it is recommended to use no more than 3 universes (510 LEDs).
LedFx users: If you want to use more than 170 LEDs, you need to go to additional settings and set "Universe Size" to 510 when adding the WLED device!
It is not recommended to try and have multiple E1.31 sources send to a single WLED controller at the same time. It will impact performance and there is no priority handling implemented. WLED is only meant to handle a single source at a time.