diff --git a/CMakeLists.txt b/CMakeLists.txt
index 1c6530734..b7cf35099 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -44,6 +44,13 @@ if(CMAKE_CXX_COMPILER_ID STREQUAL "GNU" AND CMAKE_CXX_COMPILER_VERSION
             "Building RawTherapee requires using GCC version 4.9 or higher!")
 endif()
 
+# Warning for GCC 10, which causes problems #5749:
+if(CMAKE_CXX_COMPILER_ID STREQUAL "GNU" AND CMAKE_CXX_COMPILER_VERSION VERSION_GREATER "10.0")
+    message(STATUS "WARNING: gcc ${CMAKE_CXX_COMPILER_VERSION} is known to miscompile RawTherapee when using -ftree-loop-vectorize, forcing the option to be off")    
+    set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -fno-tree-loop-vectorize")
+    set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -fno-tree-loop-vectorize")
+endif()
+
 # We might want to build using the old C++ ABI, even when using a new GCC
 # version:
 if(USE_OLD_CXX_ABI)